Melissa Benoit


Why is this medication prescribed?
Cloxacillin (Apo-cloxi®) is an antibiotic that belongs to the penicillin class of medications.  In CF, cloxacillin is used to treat lung infections caused by specific bacteria - for example Staphylococcus aureus.

How does this medication work?
Cloxacillin works by decreasing the amount of bacteria in the lungs.

What is the usual dose?
Cloxacillin is available in a tablet form. The usual dose for an adult with CF is 500 mg every 6 hours or 1 gram twice daily by mouth.

How should this medication be taken?
Take this medication on an empty stomach, at least one hour before or two hours after a meal.

Finish taking all of your medication even if you start to feel better after taking a few doses. Do not stop unless your doctor tells you to.

What should I do if I miss a dose?
Do not double any dose. If you forget to take a dose, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the next scheduled dose.

What should I expect from this medication?
You may or may not experience side effects. These side effects may disappear but let your doctor know if they are severe or if they last for more than 2 days. These include nausea, vomiting, or diarrhea, but tell us if you have any other side effects as well.

Contact your doctor as soon as possible if you experience rash, hives, difficulty breathing, or severe diarrhea.

Tell your doctor of any drug allergies and previous allergic reactions with drugs before using cloxacillin.

If you are pregnant or think you might be pregnant, talk to your doctor before starting any antibiotics.