Leila Cruikshank

Doxycycline

Why is this medication prescribed?
Doxycycline (Vibramycin®) is an oral antibiotic that belongs to the tetracycline class of medications. In CF, doxycycline is used to treat lung infections caused by specific bacteria - for example, Burkholderia cepacia.

How does this medication work?
Doxycycline works by decreasing the amount of bacteria in the lungs.

What is the usual dose?
Doxycycline is available as a capsule or tablet. A typical adult dose is 100mg twice a day by mouth.

How should this medication be taken?
To prevent the medication from being stuck in the esophagus, drink a small amount of water before and a full glass of water after each dose. Take doxycycline while sitting or standing up and do not lie down immediately afterwards. You can take this medicine with food if it upsets your stomach.

Finish taking all of your medication even if you start to feel better after taking a few doses. Do not stop unless your doctor tells you to.

Doxycycline should be stored at room temperature away from heat, moisture and direct light.

What should I do if I miss a dose?
Do not double any dose. If you forget to take a dose, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the next scheduled dose.

What should I expect from this medication?
You may or may not experience side effects. These side effects may disappear but let your doctor know if they are severe or if they last for more than 2 days. These can include nausea, diarrhea, loss of appetite, or sore mouth or gums, but tell us if you have any other side effects as well.

Contact your doctor as soon as possible if you experience rash, hives, difficulty breathing, trouble swallowing, or unusual bleeding or bruising.

Doxycycline can cause your skin to become more sensitive to sunlight. Limit the amount of time you spend in the sun until you know how this drug affects you. When you are in the sun, keep your body covered with clothing and use sunblock (preparations with zinc oxide) on exposed skin.

Precautions
Tell your doctor of any drug allergies and previous allergic reactions with drugs before using doxycycline.

If you are pregnant or think you might be pregnant, talk to your doctor before starting any antibiotics.

Doxycycline can interact with certain medications if they are taken at the same time.

If you are taking:

Antacids - take doxycycline 1 hour before or two hours after
Iron - take doxycycline 2 hours before or 3 hours after
Calcium supplements (including calcium found in milk and dairy products) - take doxycycline 1 hour before or 2 hours after
Laxatives containing magnesium - take doxycycline 1 hour before or 2 hours after